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Vitamin D and MS: Coimbra
Internist and Neurologist


Associate Professor
Department of Neurology and Neurosurgery
Federal University of Sao Paulo, UNIFESP
President, Autoimmunity Investigation and Research Institute

Laboratório de Fisiopatologia Clínica e Experimental;
Universidade Federal de São Paulo
Rua Pedro de Toledo 781 – 7 andar
04039-032 Sao Paulo SP Brazil

T +55 (11) 5539 3123

Messages from Dr. Coimbra
March 5, 2016
WARNING: "therapeutic use of Vitamin D3 is different from preventive use. The therapeutic use of this vitamin-hormone D always requires the guidance and monitoring by a physician with specific training to analyse each particular case and to determine the right dose. Otherwise there may be serious damage to health".

ATTENTION: "All patients should have periodic (at least annually) dexa scans. All those who remain sedentary will slowly loose bone mass. If they maintain a daily aerobic exercise (like 30-min brisk walking) they will steadily gain bone density.
Those high doses of vitamin D stimulate both osteoblastic and osteoclastic activities simultaneously as demonstrated by measuring P1NP and CTX respectively.
Aerobic exercise (initiated after the second medical appointment) will induce production of calcitonin and efficiently inhibit osteoclastic activity. Those disabled patients (due to neurologic disabilities or joint damage like in rheumatoid arthritis) who are therefore not capable of doing aerobic exercise should receive biphosphonates. We have used alendronate 70 mg per week. Vitamin K2 is useless under the doses of vitamin D we have employed. Aerobic exercise should start from the second medical appointment (when most fatigue is already gone). Disabling fatigue and intolerance to environmental heat affects around 80% of MS and seem to be reliable clinical index of disease activity. We always record the percentual improvement of fatigue and intolerance to heat. Patients usually start noticing reduction of fatigue around 1 month of treatment"
dr Coimbra

February 28, 2016
Dr. Cicero G. Coimbra’s Vitamin D Protocol for Multiple Sclerosis
A Message to GrassrootsHealth Participants from Dr. Coimbra
>> Video (2:28)

Vitamin D Protocol for Multiple Sclerosis 2012
by Prof. Dr Cicero Galli Coimbra
in English
Guide for patients on high doses of "VITAMIN" D
(a thorough read on these recommendations is fundamental)
>> PDF (KB)

The vitamin D revolution
by Prof. Dr Cicero Galli Coimbra
in Portugese, translate to English with Chrome
The vital importance of the hormone known as Vitamin D3 for the preservation or restoration of health.
Vitamin D3 10,000 IU daily is vital to preserve health.
>> Webpage

April 11, 2012
Vitamin D - An alternative therapy for Multiple Sclerosis
by Daniel Cunha, a patient of Dr. Cicero Galli Coimbra living with MS.
in Portuguese with English subtitles
>> Video Vitamina D - Por uma outra terapia para a Esclerose Múltipla (29:39)

April 17, 2014
Coimbra, vitamin D and autoimmune diseases
by Leonardo Rubini, a patient of Dr. Cicero Galli Coimbra.
in Italian with English subtitles
95 percent of auto-immune diseases are cured with high doses of vitamin D3.
>> Video Coimbra, vitamina D e patologie autoimmuni (1:29:13)

Questions by Leonardo Rubini
Answered by Dr. Cicero G. Coimbra

How did your protocol with high doses of Vitamin D3 come about?
What does your protocol with high doses of Vitamin D3 entail?
How many patients have you treated with your Vitamin D3 protocol and what is the success rate?
What is the success rate of you Vitamin D3 protocol for patients with multiple sclerosis?
What is the success rate for patients with chronic inflammatory bowel diseases such as ulcerative colitis and Crohn's disease?
Why haven't you tested you Vitamin D3 protocol in a RCT (randomized controlled trial)?
Are there observational studies (not double-blind or similar) published or pending, about this Vitamin D3 protocol? If not, why not?
Is the success rate for patients with psoriasis the same as for patients with Multiple Sclerosis?
What kind of neurological diseases is suitable for your Vitamin D3 protocol and how does it work?
Besides skeletal and autoimmune diseases, in which other cases your protocol can be useful?
Does your Vitamin D3 protocol also eliminate heavy metals in patients with MS, caused by an enzyme deficiency?
Is Vitamin D deficiency the cause of the inflammation and autoimmunity or is it the result of the underlying pathology?
Do you agree with the fact that measuring the parathyroid hormone (PTH) level is critical, because it is a marker used to verify the Vitamin D metabolism?
What should be the ideal level of vitamin D [25(OH)D3] and PTH in a person suffering from an autoimmune disease, and in healthy people?
What is the ideal level of PTH in the blood?
What is the best frequency of Vitamin D supplementation? Daily, weekly, monthly or yearly? And why?
Those who follow your Vitamin D3 protocol should drink at least 2.5 liters of water per day. How much should healthy people drink who only take 10,000IU per day?
How does your Vitamin D3 protocol interact with the intestinal microbiota, the digestive system and the Vitamin D Receptor (VDR)?
Why is Vitamin B2 so important in your Vitamin D3 protocol?
What is the relationship between vitamin D and phosphorus?
What is the role played by Vitamin D in clinical renal failure?
Is high Vitamin D3 intake incompatible with Glucose-6-phosphate dehydrogenase deficiency (G6PD) (favism)?
What is the relationship between Vitamin D and dystonia (a neurological movement disorder)?
Have you ever had patients with ALD (adrenoleukodystrophy) a metabolic disorder? Is it possible to treat it with your Vitamin D3 protocol?
Can a patient take Vitamin D3 and Coumadin at the same time?
Which medications are not compatible with Vitamin D3?
Do you think it is necessary to be under medical supervision when taking 10,000 IU per day?
Are you willing to come to Italy for a symposium about your protocol with high doses of vitamin D3?

Physicians interested in the Coimbra Vitamin D Protocol for Multiple Sclerosis can write to:
A list of doctors that follow the Coimbra Vitamin D Protocol.

March 2, 2016
Vitamin D3 Treatment Protocol May Put MS Patients in Remission
Vitamin D is great for prevention of disease, but what about treatment after you've been diagnosed? Since March is National Multiple Sclerosis month, now is the perfect time to bring it out into the light. The protocol we'll be highlighting in this newsletter was developed by Dr. Cicero Coimbra of Brazil.
>> GrassrootsHealth newsletter

March 7, 2016
Interview with Dr Cicero Galli Coimbra
by Dr Francisco Calvo, Clinic for Autoimmune and Chronic Diseases, Spain
in English
- Part 1 of 3: Treating MS and other Autoimmune Diseases with Vitamin D3
- Part 2 of 3: Toxicity of Vitamin D used in high doses
- Part 3 of 3: How long is the treatment?
- Part 1, 2 & 3: Treating MS and other Autoimmune Diseases with Vitamin D3

March 9, 2016
Let's Hear from the MS Community!
Maybe you don't have MS. Maybe you have another condition. We would like to hear from you! This week we are presenting two success stories from the Coimbra Protocol. Both Brazilian women. Both with long-term success.
Book: Multiple Sclerosis and (lots of) Vitamin D: My Eight-Year Treatment with The Coimbra Protocol for Autoimmune Diseases
by Ana Claudia Domene
>> GrassrootsHealth newsletter

March 16, 2016
What Does the Equator have to do with MS?
MS organizations are funding research, but it may not adequately represent vitamin D's potential. Our hope is that by this time next year we can report on a study, which will have been funded by a major MS organization, showing the efficacy of vitamin D and MS or a new standard of care to prevent MS - or as the National MS Society says - "a world free of MS." 
>> GrassrootsHealth newsletter

March 23, 2016
A Personal Study on Vitamin D and MS
This newsletter presents another perspective on how a life with MS can be bettered with vitamin D by detailing a study conducted by a researcher on herself, after being diagnosed with MS.
>> GrassrootsHealth newsletter

March 30, 2016
Here's to the end of MS!
This week's newsletter presents a final round of information on vitamin D and MS, including an interview with Dr. Reinhold Vieth, a review of the SOLAR study, and an exciting announcement about the largest managed care organization in the US recommending more sun for better health! 
>> GrassrootsHealth newsletter

September, 2016
Vitamin D – the cure for autoimmune diseases?
by David Rotter
in German
Interview with Dr Cicero Galli Coimbra
>> Webpage Vitamin D – Heilmittel für MS und Autoimmunerkrankungen?
Transcript Vitamin D – the cure for autoimmune diseases 2016.pdf
in English
>> PDF (123 KB)

Finamor DC, Sinigaglia-Coimbra R, Neves LC, Gutierrez M, Silva JJ, Torres LD, Surano F, Neto DJ, Novo NF, Juliano Y, Lopes AC, Coimbra CG. A pilot study assessing the effect of prolonged administration of high daily doses of vitamin D on the clinical course of vitiligo and psoriasis. Dermatoendocrinol. 2013 Jan 1;5(1):222-34. doi: 10.4161/derm.24808. PMID: 24494059

Fragoso YD, Adoni T, Damasceno A, de Albuquerque Damasceno CA, Ferreira ML, Finkelzstejn A, Gomes S, Goncalves MV, Grzesiuk AK, Lins S, Mendes MF, de Oliveira FT, Parolin MF, Rocha CF, Tauil CB. Unfavorable outcomes during treatment of multiple sclerosis with high doses of vitamin D. J Neurol Sci. 2014 Nov 15;346(1-2):341-2. doi: 10.1016/j.jns.2014.08.019. Epub 2014 Aug 23. No abstract available. PMID: 25183235

Kimball S, Hanwell HE, Burton JM, Heaney RP, Holick MF, Hollis B, Lewanczuk R, Makhani N, Venkateswaran S. Vitamin D supplementation in multiple sclerosis: making a case for clarity. J Neurol Sci. 2014 Dec 15;347(1-2):391-2. doi: 10.1016/j.jns.2014.10.003. Epub 2014 Oct 8. No abstract available. PMID: 25456464

Março 18, 2012
MS and other autoimmune diseases
by Daniel Cunha, a patient of Dr. Cicero Galli Coimbra
515 Testimonials
>> Website VITAMINA D - Por uma outra terapia

Janeiro 18, 2014
by Cristiane Rozicki
>> Website

Aprile 17, 2014
Leonardo Rubini
by Leonardo Rubini, a patient of Dr. Cicero Galli Coimbra
>> Website

Settembre 25, 2015
by ANNA, a patient of Dr. Cicero Galli Coimbra
Intervento del dottor Coimbra presso la Camera dei Deputati di Brasilia, la capitale federale del Brasile
>> Website

November 26, 2012
MS Cure
by a Brazilian, living in Australia and living with MS since June 2012
including 16 testimonials
>> Website

December 5, 2014
Multiple sclerosis and vitamin D
by Ana Claudia Domene, a patient of Dr. Cicero Galli Coimbra
More than six years of treatment with high doses of vitamin D for multiple sclerosis.
>> Video Esclerose Múltipla e Vitamina D

November 8, 2015
Treating Multiple Sclerosis with high doses of vitamin D under medical supervision
by a young male from Europe living with MS
My goal is to share my personal experiences with high doses of vitamin D. I genuinely want to provide hope for people who are newly diagnosed with MS and feel like their life is over. I know how it feels like to be desperate and hopeless. I am in my 20's,diagnosed with multiple sclerosis in August 2014.
>> Website

December 29, 2015
Coimbra’s Protocol Summary
by AntonioBR
Coimbra Protocol was developed by Dr. Cicero Galli Coimbra, a neurologist practicing in São Paulo, Brazil, the Coimbra Protocol is a therapeutic approach that relies on high doses of vitamin D to halt the misguided attacks of the immune system, and it has enabled thousands of patients around the world to keep their autoimmune diseases in permanent remission.
>> Website (very informative!)

February 16, 2016

Book: Multiple Sclerosis and (lots of) Vitamin D: My Eight-Year Treatment with The Coimbra Protocol for Autoimmune Diseases
by Ana Claudia Domene, a patient of Dr. Cicero Galli Coimbra
>> Kindle Edition

VitaminaD Medicina e Saude
by Dr. Wanderley Ribeiro Pires, a doctor using the Coimbra protocol
in Portuguese with English subtitles
>> Website

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Other Links
Vitamin D Wiki
- search for Coimbra
Treatment with daily high doses of vitamin D
- in Overcoming Multiple Sclerosis

FaceBook Vitamin D and MS

Page last edited: October 18, 2016
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